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Source: International Journal of Medical Sciences
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Total 5341 results found since Jan 2013.
Crosstalk between Placental Trophoblast and Decidual Immune Cells in Recurrent Miscarriage
Int J Med Sci. 2023 Jul 31;20(9):1174-1188. doi: 10.7150/ijms.86533. eCollection 2023.ABSTRACTRecurrent miscarriage (RM) is a pregnancy complication associated with dysregulation of the maternal-fetal interface. We aimed to identify dysfunctional interactions between trophoblast cells and decidual immune cells in RM. We downloaded single-cell RNA sequencing (scRNA-seq) datasets (GSE214607) from the Gene Expression Omnibus (GEO) datasets for further analysis using the R software. The data comprised of paired placental and decidual tissues, including those from patients diagnosed with RM and matched healthy controls. A total...
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Zhenzhen Liu Yao Tang Xiaoyue Zhang Jiangnan Pei Chengjie Wang Haiyan Liu Yi Yu Shouling Luo Weirong Gu Source Type: research
N-acetylcysteine improves the inhibitory effect of Quercetin-rich onion extract on HT-29 and HCT-116 colorectal cancer migration and invasion through iNOS suppression
This study demonstrated that Quercetin has higher efficacy when used in combination with NAC, representing a potential combination agent for anti-cancer drug development.PMID:37575276 | PMC:PMC10416724 | DOI:10.7150/ijms.86573
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Rataya Tanomrat Chonnapat Naktubtim Parichaya Aimvijarn Prasit Suwannalert Source Type: research
α-Mangostin Suppresses Melanoma Growth, Migration, and Invasion and Potentiates the Anti-tumor Effect of Chemotherapy
Conclusion: α-Mangostin suppresses melanoma cells growth, migration and invasion, and synergistically enhances the anti-tumor effect of chemotherapy, whose mechanism may be mediated through inhibiting Ras, PI3K and MITF.PMID:37575275 | PMC:PMC10416720 | DOI:10.7150/ijms.80940
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Yuxiu Xie Chongwen Gong Yun Xia Yuhan Zhou Ting Ye Ting Mei Hongxiang Chen Jing Chen Source Type: research
Prognostic and Clinical Implications of UNC13C expression in Hepatocellular Carcinoma Patients
Int J Med Sci. 2023 Aug 6;20(9):1235-1239. doi: 10.7150/ijms.80488. eCollection 2023.ABSTRACTAberrant expression of UNC13C (Unc-13 Homolog C) has been observed during the progression of oral squamous cell carcinoma. However, the expression pattern and clinical relevance of UNC13C in Hepatocellular carcinoma (HCC) remain to be elucidated. The purpose of this study is to examine UNC13C expression in HCC and explore its role in clinicopathological factor or prognosis in HCC. Two hundred and sixty-five patients diagnosed with HCC were included in the present study. The expression of UNC13C in HCC tissues was analyzed by immuno...
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: V Bharath Kumar Chien-Hsun Lee Tzu-Cheng Su Chia-Chieh Lin Zuhair M Mohammedsaleh Chung-Min Yeh Rudolf Kiefer Shu-Hui Lin Source Type: research
Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis
Conclusions: Our study revealed a novel lnc NR2F1-AS1/miR-25-3p/ZEB2 axis in BC metastasis and that lnc NR2F1-AS1 may serve as a potential therapeutic target for BC metastasis.PMID:37575267 | PMC:PMC10416723 | DOI:10.7150/ijms.86969
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Duanyang Zhai Yu Zhou Xiaying Kuang Fangyuan Shao Tiantian Zhen Ying Lin Qing Wang Nan Shao Source Type: research
Crosstalk between Placental Trophoblast and Decidual Immune Cells in Recurrent Miscarriage
Int J Med Sci. 2023 Jul 31;20(9):1174-1188. doi: 10.7150/ijms.86533. eCollection 2023.ABSTRACTRecurrent miscarriage (RM) is a pregnancy complication associated with dysregulation of the maternal-fetal interface. We aimed to identify dysfunctional interactions between trophoblast cells and decidual immune cells in RM. We downloaded single-cell RNA sequencing (scRNA-seq) datasets (GSE214607) from the Gene Expression Omnibus (GEO) datasets for further analysis using the R software. The data comprised of paired placental and decidual tissues, including those from patients diagnosed with RM and matched healthy controls. A total...
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Zhenzhen Liu Yao Tang Xiaoyue Zhang Jiangnan Pei Chengjie Wang Haiyan Liu Yi Yu Shouling Luo Weirong Gu Source Type: research
N-acetylcysteine improves the inhibitory effect of Quercetin-rich onion extract on HT-29 and HCT-116 colorectal cancer migration and invasion through iNOS suppression
This study demonstrated that Quercetin has higher efficacy when used in combination with NAC, representing a potential combination agent for anti-cancer drug development.PMID:37575276 | PMC:PMC10416724 | DOI:10.7150/ijms.86573
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Rataya Tanomrat Chonnapat Naktubtim Parichaya Aimvijarn Prasit Suwannalert Source Type: research
α-Mangostin Suppresses Melanoma Growth, Migration, and Invasion and Potentiates the Anti-tumor Effect of Chemotherapy
Conclusion: α-Mangostin suppresses melanoma cells growth, migration and invasion, and synergistically enhances the anti-tumor effect of chemotherapy, whose mechanism may be mediated through inhibiting Ras, PI3K and MITF.PMID:37575275 | PMC:PMC10416720 | DOI:10.7150/ijms.80940
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Yuxiu Xie Chongwen Gong Yun Xia Yuhan Zhou Ting Ye Ting Mei Hongxiang Chen Jing Chen Source Type: research
Prognostic and Clinical Implications of UNC13C expression in Hepatocellular Carcinoma Patients
Int J Med Sci. 2023 Aug 6;20(9):1235-1239. doi: 10.7150/ijms.80488. eCollection 2023.ABSTRACTAberrant expression of UNC13C (Unc-13 Homolog C) has been observed during the progression of oral squamous cell carcinoma. However, the expression pattern and clinical relevance of UNC13C in Hepatocellular carcinoma (HCC) remain to be elucidated. The purpose of this study is to examine UNC13C expression in HCC and explore its role in clinicopathological factor or prognosis in HCC. Two hundred and sixty-five patients diagnosed with HCC were included in the present study. The expression of UNC13C in HCC tissues was analyzed by immuno...
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: V Bharath Kumar Chien-Hsun Lee Tzu-Cheng Su Chia-Chieh Lin Zuhair M Mohammedsaleh Chung-Min Yeh Rudolf Kiefer Shu-Hui Lin Source Type: research
Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis
Conclusions: Our study revealed a novel lnc NR2F1-AS1/miR-25-3p/ZEB2 axis in BC metastasis and that lnc NR2F1-AS1 may serve as a potential therapeutic target for BC metastasis.PMID:37575267 | PMC:PMC10416723 | DOI:10.7150/ijms.86969
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Duanyang Zhai Yu Zhou Xiaying Kuang Fangyuan Shao Tiantian Zhen Ying Lin Qing Wang Nan Shao Source Type: research
Crosstalk between Placental Trophoblast and Decidual Immune Cells in Recurrent Miscarriage
Int J Med Sci. 2023 Jul 31;20(9):1174-1188. doi: 10.7150/ijms.86533. eCollection 2023.ABSTRACTRecurrent miscarriage (RM) is a pregnancy complication associated with dysregulation of the maternal-fetal interface. We aimed to identify dysfunctional interactions between trophoblast cells and decidual immune cells in RM. We downloaded single-cell RNA sequencing (scRNA-seq) datasets (GSE214607) from the Gene Expression Omnibus (GEO) datasets for further analysis using the R software. The data comprised of paired placental and decidual tissues, including those from patients diagnosed with RM and matched healthy controls. A total...
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Zhenzhen Liu Yao Tang Xiaoyue Zhang Jiangnan Pei Chengjie Wang Haiyan Liu Yi Yu Shouling Luo Weirong Gu Source Type: research
N-acetylcysteine improves the inhibitory effect of Quercetin-rich onion extract on HT-29 and HCT-116 colorectal cancer migration and invasion through iNOS suppression
This study demonstrated that Quercetin has higher efficacy when used in combination with NAC, representing a potential combination agent for anti-cancer drug development.PMID:37575276 | PMC:PMC10416724 | DOI:10.7150/ijms.86573
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Rataya Tanomrat Chonnapat Naktubtim Parichaya Aimvijarn Prasit Suwannalert Source Type: research
α-Mangostin Suppresses Melanoma Growth, Migration, and Invasion and Potentiates the Anti-tumor Effect of Chemotherapy
Conclusion: α-Mangostin suppresses melanoma cells growth, migration and invasion, and synergistically enhances the anti-tumor effect of chemotherapy, whose mechanism may be mediated through inhibiting Ras, PI3K and MITF.PMID:37575275 | PMC:PMC10416720 | DOI:10.7150/ijms.80940
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Yuxiu Xie Chongwen Gong Yun Xia Yuhan Zhou Ting Ye Ting Mei Hongxiang Chen Jing Chen Source Type: research
Prognostic and Clinical Implications of UNC13C expression in Hepatocellular Carcinoma Patients
Int J Med Sci. 2023 Aug 6;20(9):1235-1239. doi: 10.7150/ijms.80488. eCollection 2023.ABSTRACTAberrant expression of UNC13C (Unc-13 Homolog C) has been observed during the progression of oral squamous cell carcinoma. However, the expression pattern and clinical relevance of UNC13C in Hepatocellular carcinoma (HCC) remain to be elucidated. The purpose of this study is to examine UNC13C expression in HCC and explore its role in clinicopathological factor or prognosis in HCC. Two hundred and sixty-five patients diagnosed with HCC were included in the present study. The expression of UNC13C in HCC tissues was analyzed by immuno...
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: V Bharath Kumar Chien-Hsun Lee Tzu-Cheng Su Chia-Chieh Lin Zuhair M Mohammedsaleh Chung-Min Yeh Rudolf Kiefer Shu-Hui Lin Source Type: research
Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis
Conclusions: Our study revealed a novel lnc NR2F1-AS1/miR-25-3p/ZEB2 axis in BC metastasis and that lnc NR2F1-AS1 may serve as a potential therapeutic target for BC metastasis.PMID:37575267 | PMC:PMC10416723 | DOI:10.7150/ijms.86969
Source: International Journal of Medical Sciences - August 14, 2023 Category: Biomedical Science Authors: Duanyang Zhai Yu Zhou Xiaying Kuang Fangyuan Shao Tiantian Zhen Ying Lin Qing Wang Nan Shao Source Type: research
